Malignant human renin producing paraganglionoma-localization with 123I-MIBG and treatment with 131I-MIBG

Autor:	S, Arver, H, Jacobsson, B, Cedermark, B, Hamberger, G, Lundell, L, Grimelius, K, Brismar
Rok vydání:	1999
Předmět:	Adult Iodine Radioisotopes Paraganglioma 3-Iodobenzylguanidine Fatal Outcome Renin Adrenal Gland Neoplasms Humans Female Radiopharmaceuticals Radionuclide Imaging Neoplasm Proteins
Zdroj:	Clinical endocrinology. 51(5)
ISSN:	0300-0664
Popis:	A 22-year-old woman presenting severe hypertension and hypokalaemia is described. Initial evaluation showed a large tumour localized at the position of the left adrenal gland. Subsequent surgery temporarily relieved all signs and symptoms caused by the tumour. The symptoms relapsed after a 2-year disease-free interval. At re-evaluation, the tumour was shown to produce an uncontrolled secretion of renin, thus triggering aldosterone-dependent hypertension. This report describes the diagnosis, treatment and clinical course of this unique patient with a malignant paraganglionoma of adrenal origin.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a5bfb62bdea9bcb22a3b4657cccb8bcf https://pubmed.ncbi.nlm.nih.gov/10594525 Zobrazit plný text záznamu Plný text