[Cytogenetic study of acute and chronic leukemias]

Autor: G, Conte, M, Torrens, C, Larraín, C, Be, V, Daher, R, Youlton
Rok vydání: 1989
Předmět:
Zdroj: Revista medica de Chile. 117(2)
ISSN: 0034-9887
Popis: From 1983 to 1987 we studied 30 patients with leukemia searching for chromosomal alterations. Cytogenetic studies of bone marrow showed an abnormal karyotype in 19 (67%). Seven out of 14 cases of acute leukemia presented different chromosomic alterations. The Philadelphia chromosome was found in 11 patients with chronic myeloid leukemia and 3 patients with chronic lymphatic leukemia; a Pseudo-Philadelphia chromosome was present in one patient, this being the first such finding in Chile. Thus, the karyotype is a valuable complementary study not only in chronic myeloid leukemia but also in chronic lymphatic leukemia and the acute lymphoblastic and non-lymphoblastic varieties.
Databáze: OpenAIRE