| Autor: |
Yuko, Matsushima, Ryohei, Kawabata, Hiroshi, Imamura, Tomono, Kishimoto, Yoshimi, Hachino, Yukako, Yasui, Misako, Fujino, Chika, Fujii, Mutsumi, Fukunaga, Hiroki, Ohzato, Hiroshi, Furukawa |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 39(6) |
| ISSN: |
0385-0684 |
| Popis: |
We investigated the efficacy of gastrojejunostomy followed by S-1-based chemotherapy for unresectable gastric cancer with pyloric stenosis. We performed gastrojejunostomy and S-1-based chemotherapy in 14 unresectable gastric cancer patients with gastric outlet obstructions between April 2006 and June 2010. Although there were two complications after surgery, no treatment-related deaths were observed. The response rate of the S-1-based chemotherapy was 41.7%, and the median survival after surgery was 12.3 months. All patients were tolerating a regular diet and a significant improvement in oral intake lasted for at least 6 months. In conclusion, gastrojejunostomy followed by chemotherapy with S-1 appears to be an effective treatment modality for unresectable gastric cancer with pyloric stenosis. It enables us to practice S-1-based standard chemotherapy for advanced gastric cancer and improve the quality of life of patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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