| Autor: |
Zhan-lu, Li, Bin-quan, Zhou, Jun-hui, Zhu, Guo-sheng, Fu |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 40(6) |
| ISSN: |
1008-9292 |
| Popis: |
To determine the effect of proton pump inhibitor (PPI) on in-stent restenosis (ISR) in patients receiving clopidogrel therapy.Total 439 patients underwent percutaneous coronary intervention (PCI) were enrolled in the study,including 250 post-PCI patients discharged on clopidogrel alone and 189 patients discharged on clopidogrel with PPI. The in-stent restenosis (ISR) ratio of the patients in these two groups were observed.During a mean follow-up period of (13 ± 5.9) months, the post-PCI patients discharged on concomitant clopidogrel-PPI therapy had higher risk of ISR than those discharged on clopidogrel alone (19.6% Compared with 8%, P0.001).Concomitant use of clopidogrel and PPI after hospital discharge would increase the risk of ISR for post-PCI patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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