[Probiotics for the prevention of antibiotic-induced diarrhea]

Autor: A, Eser, F, Thalhammer, F, Burghuber, C, Högenauer, F, Stockenhuber, C, Wenisch, K, Widhalm, W, Reinisch
Jazyk: němčina
Rok vydání: 2012
Předmět:
Zdroj: Zeitschrift fur Gastroenterologie. 50(10)
ISSN: 1439-7803
Popis: Between 5 and 49% of patients treated with antibiotics suffer from diarrhoea. Principally all microbial agents can cause diarrhoea, especially oral agents like cephalosporines, clindamycin, broad-spectrum penicillins, and quinolones of the 3 rd and 4th generation. Manifestations of antibiotic-associated diarrhoea range from mild self-limiting forms to severe life-threatening courses. The potentially most severe form of antibiotic-associated diarrhoea is caused by Clostridium diffcile accounting for approx. 25 % of antibiotic-associated diarrhoea. In the past two decades a broad spectrum of different probiotic strains has been evaluated for the primary prevention of antibiotic-associated diarrhoea in children and adults. Based on their efficacy and clinical data, different levels of evidence and recommendations are emerging on the preventive use of probiotics in antibiotic-associated diarrhoea.
Databáze: OpenAIRE