Molecular and biological features of Culex quinquefasciatus homozygous larvae for two cqm1 alleles that confer resistance to Lysinibacillus sphaericus larvicides

Autor:	Heverly Suzany G, Menezes, Nathaly A, Nascimento, Milena, Paiva-Cavalcanti, Samara G, da Costa-Latgé, Fernando A, Genta, Cláudia Mf, Oliveira, Tatiany P, Romão, Maria Helena Nl, Silva-Filha
Rok vydání:	2021
Předmět:	Culex Larva Bacterial Toxins Animals Insect Proteins alpha-Glucosidases Bacillaceae Alleles
Zdroj:	Pest management scienceREFERENCES. 77(7)
ISSN:	1526-4998
Popis:	Culex quinquefasciatus resistance to the binary toxin from Lysinibacillus sphaericus larvicides can occur because of mutations in the cqm1 gene that prevents the expression of the toxin receptor, Cqm1 α-glucosidase. In a resistant laboratory-selected colony maintained for more than 250 generations, cqm1Homozygous larvae for each allele were compared. Both larvae displayed the same level of resistance to the binary toxin (3500-fold); therefore, a change in phenotype was not the reason for the replacement observed. The lack of Cqm1 expression did not reduce the total specific α-glucosidase activity for homozygous cqm1Homozygous larvae for each allele exhibited a similar resistant phenotype. However, they presented specific advantages that might favor their selection and can be used in designing resistance management practices. © 2021 Society of Chemical Industry.
Databáze:	OpenAIRE
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