Variability in Intrahousehold Transmission of Ebola Virus, and Estimation of the Household Secondary Attack Rate
| Autor: | Judith R, Glynn, Hilary, Bower, Sembia, Johnson, Cecilia, Turay, Daniel, Sesay, Saidu H, Mansaray, Osman, Kamara, Alie Joshua, Kamara, Mohammed S, Bangura, Francesco, Checchi |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Adolescent viruses macromolecular substances Sierra Leone Young Adult Major Articles and Brief Reports Risk Factors secondary attack rate Disease Transmission Infectious Humans Child Aged Aged 80 and over Family Health Family Characteristics transmission chains Infant Newborn virus diseases Infant Hemorrhagic Fever Ebola Middle Aged intrahousehold Child Preschool Viruses Ebola Female |
| Zdroj: | The Journal of Infectious Diseases |
| ISSN: | 1537-6613 |
| Popis: | In a study of 94 Ebola-affected households, intrahousehold transmission was very variable, with more transmission from those with more severe disease and from older cases. The household secondary attack rate was 18%. Transmission between family members accounts for most Ebola virus transmission, but little is known about determinants of intrahousehold spread. From detailed exposure histories, intrahousehold transmission chains were created for 94 households of Ebola survivors in Sierra Leone: 109 (co-)primary cases gave rise to 317 subsequent cases (0–100% of those exposed). Larger households were more likely to have subsequent cases, and the proportion of household members affected depended on individual and household-level factors. More transmissions occurred from older than from younger cases, and from those with more severe disease. The estimated household secondary attack rate was 18%. |
| Databáze: | OpenAIRE |
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