[Complete treatment of basal cell carcinoma; cost effectiveness of Mohs micrographic surgery versus conventional excision]

Autor: J M, Muche, A, van Rengen, K, Mosterd
Jazyk: Dutch; Flemish
Rok vydání: 2018
Předmět:
Zdroj: Nederlands tijdschrift voor geneeskunde. 161
ISSN: 1876-8784
Popis: To investigate whether Mohs micrographic surgery (MMS) in accordance with the indications in the revised guideline on basal cell carcinoma (BCC) more often leads to complete treatment than conventional excision (CE) and whether the costs are comparable, and to analyse whether this also applies to all primary BCC of the face.Retrospective analysis.We gathered data on 3374 MMS procedures and calculated per localisation, subtype and size: the percentage of CE that would have been incomplete after applying the recommended surgical margin; the surgical margin necessary to achieve complete excision in90% of cases; the final defect after CE and after MMS; the cost of MMS and the cost of CE with postponed reconstruction or, in the case of incomplete CE, subsequent MMS.For the new MMS indications we can show that using MMS seems to prevent incomplete CE in 12-45% of cases. CE will also lead to incomplete excision in ≥ 10% of cases in most subgroups of primary facial BCC, with the exception of some small superficial or nodular BCCs in the H-zone. The final defect was always smaller after MMS than after CE. MMS can be used with comparable costs for primary BCCs5 mm in the H-zone and20 mm elsewhere in the face.The surgical margins recommended in the guidelines are inadequate to achieve complete excision rates in90% of facial CEs. MMS is an efficient alternative for CE for primary BCCs5 mm in the H-zone and20 mm elsewhere in the face.
Databáze: OpenAIRE