Autor: |
I V, Fel'dblium, N N, Vorob'eva, A M, Nikolaeva, V N, Borisova, V A, Mel'nikov, M V, Budanov, I A, Iakovleva, A V, Kaz'ianin, E V, Pushkareva, D V, Griaznova, N V, Shalunova, O V, Perelygina, N A, Ozeretskovskiĭ, T A, Bektimirov, N V, Isaeva |
Rok vydání: |
2002 |
Předmět: |
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Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (5) |
ISSN: |
0372-9311 |
Popis: |
Bubo-M, the first Russian associated vaccine, was found to have low reactogenicity and high immunogenic potency. The frequency of postvaccinal reactions in the group of persons immunized with Bubo-M (20%) appeared to be considerably lower than among persons who received the combined injection of adsorbed DT toxoid with reduced antigen content and vaccine against hepatitis B (47.7%). Following the course of vaccination the level of anti-HBs considerably exceeded the protective level. Immune response to the diphtheria and tetanus components of Bubo-M exceeded that observed after immunization with absorbed DT toxoid with reduced antigen content (p0.05). |
Databáze: |
OpenAIRE |
Externí odkaz: |
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