| Autor: |
S, Rajendran, K, Parasakthy, P D, Deepalakshmi, S N, Devaraj |
| Rok vydání: |
1996 |
| Předmět: |
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| Zdroj: |
Indian journal of experimental biology. 34(1) |
| ISSN: |
0019-5189 |
| Popis: |
A crude extract containing some toxic furanoterpenoids was isolated from F. solani infected sweet potatoes. Chronic administration of the crude extract to male albino rats at a dosage of 1 mg/kg body weight/day for 21 days brought about a sharp increase in the thiobarbituric acid reactive substances and a depression of glutathione levels in the lung and liver homogenates. The antioxidant defense system was affected as evident from a significant fall in the activities of the enzymes, superoxide dismutase, catalase, glutathione peroxidase, glucose-6-phosphate dehydrogenase and glutathione-S-transferase. Such an alteration could be the reason for the lung and liver damage caused by these toxic furanoterpenoids. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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