| Autor: |
M L, Libe, V I, Brusovanik, I P, Levshina |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 115(4) |
| ISSN: |
0365-9615 |
| Popis: |
Pathological and adaptive-compensatory alterations of rat cerebral cortical beta-adrenergic receptors have been demonstrated using the model of experimental neurosis developing as a result of chronic emotional painful stress. After the first week of stress increases of both Kd and Bmax occur; both indexes reach control levels after 3 weeks of neurotization. The changes of cortical beta-adrenoreceptors accompany transient fall of cholesterol-to-phospholipid ratio and decrease of free radical lipid oxidation in brain cortex. The normalization of all cerebral parameters after 3 weeks of stress coincides with the activation of lipid peroxidation in blood serum. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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