Prevalence of coronary risk factors and myocardial perfusion scintigraphy abnormalities in asymptomatic diabetic outpatients
| Autor: | Francisco das Chagas, Monteiro, Fhabyula da Silva, Cunha, Natalino, Salgado Filho, José Bonifácio, Barbosa, João Ribeiro, Furtado, Pedro Antônio Muniz, Ferreira, Vinícius, Nina, Joyce, Lages, Nilton, Santana |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Technetium Tc 99m Sestamibi Cholesterol HDL Myocardial Infarction Heart Cholesterol LDL Coronary Artery Disease Middle Aged Sex Factors Diabetes Mellitus Type 2 Outpatients Humans Mass Screening Female Radiopharmaceuticals Epidemiologic Methods Radionuclide Imaging Brazil Diabetic Angiopathies Aged |
| Zdroj: | Arquivos brasileiros de cardiologia. 89(5) |
| ISSN: | 1678-4170 |
| Popis: | To determine the prevalence of coronary artery disease (CAD) risk factors (RF) and myocardial ischemia in a sample of asymptomatic diabetic patients treated on an outpatient basis.From 80 type 2 diabetic patients initially recruited at an university outpatient endocrinology clinic, with no symptoms and/or CAD diagnosis, only 61 patients completed the study protocol, being 52,5% females, with a mean age of 56.3 +/- 10.9 years. The patients were interviewed searching for RF and underwent electrocardiogram, echocardiogram and perfusional myocardial scintigraphy (PMS) at rest and under stress. According to the PMS results they were divided into two groups: an ischemic and a normal one .The RF identified were: male gender (48%), ageor = 55 years (51%), family history of premature atherosclerotic disease (16%), history of smoking (46%), hypertension (44%), sedentary lifestyle (62%), overweight/obesity (67%), HDL- cholesterol45 mg/dl (69%), LDL- cholesterolor = 100 mg/dl (85%) and triglyceridesor = 150 mg/dl (54%). Ischemic MPS were diagnosed in 15% of the patients. The variables associated with this diagnosis were: male gender (p=0.007), low HDL levels (p=0.046), history of smoking (p=0.038), left ventricular hypertrophy (LVH) (p=0.043) and left ventricle ejection fraction (LVEF)60% (p=0.01).A high prevalence of associated RF was observed, as well as a significant prevalence of 15% for myocardial ischemia. The variables identified as predictors of a myocardial ischemia diagnosis were: male gender, low HDL-cholesterol, past smoking, LVH and LVEF60%. |
| Databáze: | OpenAIRE |
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