Long-term survival in a child with a central nervous system medulloepithelioma

Autor: Parham, Moftakhar, Xuemo, Fan, Carole H, Hurvitz, Keith L, Black, Moise, Danielpour
Rok vydání: 2008
Předmět:
Zdroj: Journal of neurosurgery. Pediatrics. 2(5)
ISSN: 1933-0707
Popis: Central nervous system medulloepitheliomas are extremely rare and malignant (World Health Organization Grade IV) primitive neuroectodermal tumors (PNETs) that arise in childhood. Unlike other PNETs, medulloepitheliomas have a dismal prognosis, with only 2 reported cases in the literature in which the patient survived beyond 5 years after treatment. The authors report on the third known case of a child who survived longer than 5 years. A review of all the published cases of medulloepithelioma is also presented, and alternative treatment strategies for PNET tumors, including high-dose chemotherapy with stem-cell rescue, are discussed.
Databáze: OpenAIRE