Testing the statistical certainty of a response to increasing doses of a drug

Autor: J W, Tukey, J L, Ciminera, J F, Heyse
Rok vydání: 1985
Předmět:
Zdroj: Biometrics. 41(1)
ISSN: 0006-341X
Popis: Experiments in which the treatments are composed of a series of doses of a compound and a zero dose control are often used in animal toxicity studies. A test procedure is proposed to assess trends in the response variable. The notion of a no-statistical-significance-of-trend (NOSTASOT) dose is introduced, and questions of multiplicity of statistical tests in this context are addressed.
Databáze: OpenAIRE