Synthesis and characterization of hybrid Anderson hexamolybdoaluminates(III) functionalized with indometacin or cinnamic acid
| Autor: | Gumerova, Nadiia I., Blazevic, Amir, Caldera Fraile, Tania, Roller, Alexander, Giester, Gerald, Rompel, Annette |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Acta Crystallographica. Section C, Structural Chemistry |
| ISSN: | 2053-2296 |
| Popis: | A post-functionalization protocol was used for the synthesis of two new tris-hybrid Al-centred Anderson-type polyoxomolybdates with indometacin or cinnamic acid. The single-side Al-centred tris-functionalized hybrid organic–inorganic Anderson polyoxomolybdates (C16H36N)3[Al(OH)3Mo6O18(OCH2)3CNH(C10H8O)]·C9H7N·4CH3OH·5H2O (AlMo6-NH-Cin; Cin is cinnamic acid, C10H9O2) and (C16H36N)3[Al(OH)3Mo6O18(OCH2)3CNH(C19H15ClNO3)]·9H2O (AlMo6-NH-Indo; Indo is indometacin, C19H16ClNO4) have been prepared in a mild three-step synthesis and structurally characterized by single-crystal X-ray diffraction, 1H NMR and IR spectroscopies and elemental analysis. Both AlMo6-NH-Cin and AlMo6-NH-Indo crystallize in the orthorhombic space group Pbca. The antibacterial activities of AlMo6-NH-Cin and AlMo6-NH-Indo against the Gram-negative human mucosal pathogen Moraxella catarrhalis were investigated by determination of the minimum inhibitory concentration, which is 32 µg ml−1 for AlMo6-NH-Cin and 256 µg ml−1 for AlMo6-NH-Indo. |
| Databáze: | OpenAIRE |
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