| Autor: |
Su-fang, Han, Yang-qiu, Li, Li-jian, Yang, Shao-hua, Chen, Wei-wei, Liu, Zhen-qian, Huang, Jin-ming, Wu, Jia-yu, Chen |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 22(3) |
| ISSN: |
1001-9391 |
| Popis: |
To analyze the content of signal joint T-cell receptor excision DNA circles signal joint T-cell receptor excision DNA circles (sjTRECs) within peripheral blood mononuclear cells (PBMCs), thereby to infer the level of naive T cells and the recent thymic output function in benzene-exposed workers.Quantitative detection of sjTRECs in DNA of peripheral blood mononuclear cells from 11 normal individuals and 62 benzene-exposed workers were performed by real-time polymerase chain reaction (PCR) and TaqMan technique.The median value of sjTRECs copies/1,000 PBMCs was 7.81 in normal individuals whereas it was 2.56 copies/1 000 PBMCs in age-unadjusted benzene-exposed workers (P0.01). And its levels were obviously different between two different age groups: that in 30-year-old group (1.76 copies/1,000 PBMCs, n = 23) was less thanor= 30-years-old group (3.19 copies/1,000 PBMCs, n = 39, P0.05).Benzene exposure may influence the recent thymic output function, and the sjTRECs levels may relate with the age of benzene-exposed workers. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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