| Autor: |
M H, Tay, C, Balram, K F, Foo, I, Busmanis, S, Raman, K S, Khoo |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
Annals of the Academy of Medicine, Singapore. 32(1) |
| ISSN: |
0304-4602 |
| Popis: |
We report a patient with bowel infarction due to invasive Aspergillus infection as a result of prolonged chemotherapy-induced neutropenia.The patient was given neoadjuvant chemotherapy with doxorubicin, docetaxel, and capecitabine for a breast tumour. She developed prolonged neutropenia, Escherichia coli and Candida krusei sepsis, acute arterial thrombosis of the left lower limb, and invasive aspergillus infection.She underwent a subtotal colectomy, small intestine resection and an above-knee amputation.The hospitalisation was complicated with methicillin-resistant Staphylococcus aureus pneumonia and short gut syndrome. She subsequently underwent simple mastectomy with axillary clearance and received adjuvant chemotherapy and radiation without complication.Chemotherapy should be protocol-directed. In a non-trial situation, protocol must have a sound basis, proven safety, and efficacy. Aspergillus infection is uncommon in patients with solid tumours; prompt treatment must be started on high suspicion. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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