[Comparative biochemical and electron microscopic research on the membrane-damaging action of a chemical carcinogen on the endoplasmic reticulum in vivo and in vitro]

Autor:	R V, Merkur'eva, S I, Dolinskaia, A B, Shekhtman, T G, Gasanov, T I, Gadzhieva
Rok vydání:	1987
Předmět:	Male Microscopy Electron Time Factors Liver Animals Humans Amnion Glucosephosphate Dehydrogenase Glucuronosyltransferase Endoplasmic Reticulum Cells Cultured Dimethylnitrosamine Rats
Zdroj:	Biulleten' eksperimental'noi biologii i meditsiny. 103(2)
ISSN:	0365-9615
Popis:	The results of a comparative biochemical and electron-microscopic study of membrane-injuring effect of N-nitrosodimethylamine--a chemical carcinogen widespread in the environment are reviewed. It has been established that in vivo and in vitro membrane-injuring effect of nitrosodimethylamine is characterized by reduced activity of membrane-bound enzymes of endoplasmic reticulum (UDP-glucuronyltransferase and glucose-6-phosphatase) accompanied by alterations in functional morphology of cells and intracellular structure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a381021c1b21908edff309811514c8c0 https://pubmed.ncbi.nlm.nih.gov/3101762 Zobrazit plný text záznamu