From unicuspid to quadricuspid: influence of aortic valve morphology on aortic three-dimensional hemodynamics
| Autor: | Pegah, Entezari, Susanne, Schnell, Riti, Mahadevia, Chris, Malaisrie, Patrick, McCarthy, Marla, Mendelson, Jeremy, Collins, James C, Carr, Michael, Markl, Alex J, Barker |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Heart Valve Diseases Myocardial Perfusion Imaging Magnetic Resonance Imaging Cine Reproducibility of Results Image Enhancement Multimodal Imaging Sensitivity and Specificity Article Cohort Studies Young Adult Imaging Three-Dimensional Bicuspid Aortic Valve Disease Aortic Valve Subtraction Technique Image Interpretation Computer-Assisted Humans Female Blood Flow Velocity Magnetic Resonance Angiography |
| Zdroj: | Journal of magnetic resonance imaging : JMRI. 40(6) |
| ISSN: | 1522-2586 |
| Popis: | To assess the impact of aortic valve morphology on aortic hemodynamics between normal tricuspid and congenitally anomalous aortic valves ranging from unicuspid to quadricuspid morphology.Aortic three-dimensional (3D) blood flow was evaluated by 4D flow MRI in 14 healthy volunteers with normal trileaflet valves and 14 patients with unicuspid (n = 3), bicuspid (n = 9, 3 "true" bicuspid, 3 right-left (RL), 3 right-noncoronary (RN) leaflet fusion, and quadricuspid aortic valves (n = 2). Data analysis included the co-registered visualization of aortic valve morphology with systolic 3D blood flow. The influence of valve morphology on aortic hemodynamics was quantified by valve flow angle.All RL-bicuspid aortic valve (BAV) were associated with flow jets directed toward the right anterior aortic wall while RN-fusion and unicuspid valves resulted in flow jet patterns toward the right-posterior or posterior wall. Flow angles were clearly influenced by valve morphology (47° ± 10, 28° ± 2, 29° ± 18, 18° ± 12, 15° ± 2 for unicuspid, true BAV, RN-BAV, RL-BAV, quadricuspid valves) and increased compared with controls (7.2° ± 1.1, P = 0.001).Altered 3D aortic hemodynamics are impacted by the morphology of congenitally malformed aortic valves. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text