MTA-Based Cements: Biocompatibility and Effects on the Gene Expression of Collagen Type 1 and TGF

Autor:	Diana María, Escobar-García, María Guadalupe, Medina-Rosas, Ana María, González-Amaro, Verónica, Méndez-González, Héctor, Flores, Amaury, Pozos-Guillén
Rok vydání:	2022
Předmět:	Root Canal Filling Materials Transforming Growth Factor beta1 Drug Combinations Silicates Materials Testing Gene Expression Humans Oxides Pemetrexed Calcium Compounds Aluminum Compounds Collagen Type I
Zdroj:	BioMed research international. 2022
ISSN:	2314-6141
Popis:	This study sought to evaluate the biocompatibility of Neomineral Trioxide Aggregate (Neo-MTA), MTA Repair High Plasticity (MTA-HP), and Mineral Trioxide Aggregate-Angelus white (MTA-Ang) in fibroblasts of human dental pulp.Morphology was evaluated after 24 h of incubation.Morphological changes were observed in all groups. Neo-MTA and MTA-Ang were associated with increased cell viability, and all materials induced apoptosis, with a higher percentage in the MTA-HP group than in the other groups. In the LIVE/DEAD assay, there was more damage to the cell membrane in the group of cells treated with MTA-HP than in the other groups.Neo-MTA and MTA-Ang presented similar biocompatibility, and both showed greater biocompatibility than MTA-HP. MTA-HP and MTA-Ang increased Col-1A gene expression, and Neo-MTA and MTA-Ang increased TGF
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a368139f4a8756ab1585665205b79ad3 https://pubmed.ncbi.nlm.nih.gov/35402617 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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