[Colonic perforation in a patient treated with combination chemotherapy for recurrent ovarian clear cell adenocarcinoma]
| Autor: | Kohei, Shitara, Masaki, Munakata, Atsushi, Ishiguro, Toshihiro, Kudo, Ritsuko, Okada, Rumiko, Tomioka, Sumako, Mitobe, Shin, Yokoyama, Yuh, Sakata |
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| Rok vydání: | 2006 |
| Předmět: |
Ovarian Neoplasms
Lung Neoplasms Colonoscopy Middle Aged Irinotecan Drug Administration Schedule Pleural Effusion Malignant Fatal Outcome Intestinal Perforation Antineoplastic Combined Chemotherapy Protocols Cecal Diseases Drainage Humans Camptothecin Female Cisplatin Neoplasm Recurrence Local Adenocarcinoma Clear Cell |
| Zdroj: | Gan to kagaku ryoho. Cancerchemotherapy. 33(10) |
| ISSN: | 0385-0684 |
| Popis: | Colonic perforation due to colitis is a known and reported side effect of chemotherapy.A 53-year-old woman was treated with combination chemotherapy of irinotecan plus cisplatin for a recurrent ovarian clear cell adenocarcinoma. Steroid was also used for suspected interstitial pneumonia. After two cycles of treatment, she developed a colonic perforation. Emergency laparotomy was not performed because of poor performance status with multiple lung metastases, pleural effusion and pericardial effusion. Colonoscopy showed a perforated wall at the cecum, and a long tube with balloon was inserted for occlusion. In addition, a peritoneal drainage tube was inserted. Oral intake could be restarted for a while, but she died from tumor progression one and a half months after the diagnosis of perforation.Non-surgical management with peritoneal drainage and ileus tube was useful in this case of colonic perforation for preserving oral intake and quality of life. |
| Databáze: | OpenAIRE |
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