| Autor: |
M P, Pavlovskiĭ, O M, Oborin, Iu E, Lille, M I, Lopp, R M, Zubachik |
| Rok vydání: |
1994 |
| Předmět: |
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| Zdroj: |
Klinicheskaia khirurgiia. (11) |
| Popis: |
The new synthetic analogue of prostaglandin I2 (prostacyclin MM-706) influence on some hepatic function indexes was studied up in 7 dogs with an acute hepatic insufficiency caused by severe hemorrhagic shock. Rapid and steady normalization of indexes and the animals survival were promoted by intravenous infusion of MM-706 given in 300 ng/kg dose together with hemocorrector named lactoprotein given in 10 ml/kg dose (7,5 +/- 1,4) hours later. Possible action mechanisms of the MM-706 therapeutic efficacy are considered. Results of investigation performed constitute an experimental base of the MM-706 application in the complex treatment of an acute hepatic insufficiency of different genesis in the clinic. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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