Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial

Autor:	Hyman, Engelberg
Rok vydání:	2004
Předmět:	Amyloid beta-Peptides Heparin Dementia Vascular Hemodynamics Brain Intracranial Arteriosclerosis Protein Structure Secondary Lipoprotein Lipase Oxidative Stress Fibrinolytic Agents Alzheimer Disease Humans Chemokines Reactive Oxygen Species Aged Peptide Hydrolases
Zdroj:	Dementia and geriatric cognitive disorders. 18(3-4)
ISSN:	1420-8008
Popis:	The following areas are discussed in this review: atherogenesis; cerebrovascular factors; hypoperfusion; beta-amyloid production; beta-amyloid fibril formation; beta-sheets; metal cations; reactive oxygen species/free radicals; chronic inflammatory factors; endogenous plasma heparin; lipoprotein lipase; polyamines; protein kinase C; casein kinases; phospholipase A2; serine proteases; myeloperoxidase; cyclooxygenase 2; cysteine proteases; caspases; proprotein convertases; aspartic proteases; cyclin proteinases; thrombin; tau hyperphosphorylation; advanced glycosylation end products; activator protein 1; calcium; apolipoprotein E epsilon4; histamine; blood-brain barrier; glutamate; transglutaminase; insulin-like growth factor 1.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a213b41e3e77ae0fa92afb9542aa6f73 https://pubmed.ncbi.nlm.nih.gov/15286460 Zobrazit plný text záznamu