| Autor: |
Leonardo S, Lino-Silva, Miguel A, García-Gómez, José M, Aguilar-Romero, Jorge A, Domínguez-Rodríguez, Rosa A, Salcedo-Hernández, Reynaldo, Loaeza-Belmont, Erika B, Ruiz-García, Ángel, Herrera-Gómez |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Journal of surgical oncology. 112(8) |
| ISSN: |
1096-9098 |
| Popis: |
We aimed to determine the prognostic value of the mesorectum quality assessed in a two-grade system compared with a classic system.Consecutive patients undergoing surgery for rectal cancer were included (n = 103). Mesorectum was assessed into three grades (classic system: complete, nearly complete, incomplete) and compared with a two-grade system (adequate, inadequate).Mesorectum was complete in 62 (60.25%) patients, nearly complete in 21, and incomplete in 20. Reassessment showed adequate mesorectum in 83 (80.5%) patients and inadequate in 20. A R0 resection was achieved in 90.4% of adequate mesorectum and in 65% of inadequate mesorectum (P = 0.006). Recurrence was present in 18% of adequate mesorectum patients as compared with 50% of inadequate mesorectum (P = 0.003). The classic system failed to accurately predict the 5-year survival rate between complete (78.9%) and nearly complete (86.2%) categories (P = 0.235); whereas a two grading system showed a 5-year survival rate of 80.8% for adequate versus 39.3% for inadequate (P = 0.034).High recurrence occurred in inadecuate mesorectum patients and was correlated with R1/R2 resections, positive margins, and decreased survival. We propose a simplified classification of mesorectum that correlates with survival and overall recurrence. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text