| Autor: |
Parul, Benien, Mohammed, Almuteri, Shrey, Shah, Mark, Böhlke, Ahmed, Mehanna, Gerard G M, D'Souza |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Methods in molecular biology (Clifton, N.J.). 2275 |
| ISSN: |
1940-6029 |
| Popis: |
Surface modification of liposomes with a ligand is facilitated by the conjugation of the ligand to a hydrophobic molecule that serves to anchor the ligand to the liposomal bilayer. We describe here a simple protocol to conjugate a triphenylphosphonium group to several commercially available functionalized phospholipids. The resulting triphenylphosphonium-conjugated lipids can be used to prepare liposomes that preferentially associate with mitochondria when exposed to live mammalian cells in culture. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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