| Autor: |
A, Siemieniuk, H, Szałkowska-Pagowska, S, Lochyński, K, Piatkowski, B, Filipek, J, Krupińska, R, Czarnecki, T, Librowski, K, Zebala |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Polish journal of pharmacology and pharmacy. 44(4) |
| ISSN: |
0301-0244 |
| Popis: |
Esters of N,N-diethylaminoacetic acid and hydroxyamines, obtained from structurally different natural monoterpenes, were pharmacologically examined. It was proved that salts of the obtained compounds had local anesthetic properties in infiltration anesthesia, compounds 9, 6 and 8 having been more potent than lidocaine. Compounds 7-9 slightly increased the arrhythmogenic dose, and compound 12 - the lethal dose of strophanthin. All the examined compounds transiently decreased the arterial blood pressure and displayed a cardiopressive activity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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