[Lymphocytes with receptors to streptococcal polysaccharide group A in the thymus of rheumatism patients. Change in the response of normal thymocytes to adenosine, theophylline and decantate]

Autor: E V, Gnezditskaia, E A, Bazanova, V P, Bukhova
Rok vydání: 1993
Předmět:
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny. 115(3)
ISSN: 0365-9615
Popis: With the help of immunomodulators (adenosine, theophylline, levamisole) and decantat of 3-hour culture of normal thymocytes, the features of thymocytes with the receptor for polysaccharide of streptococcus group A(A-PSC) (R = PSC+cells) in patients with rheumatism. It has been established that in patients' thymus the quantity of lymphocytes, able to express R-PSC (predecessors of R = PSC + cells) decreased under the influence of theophylline and adenosine. The predecessors of R = PSC+thymocytes in the majority of patients with rheumatism are areactive to decantat action. Moreover R = PSC+cells in comparison with normal ones lose this receptors under it's influence.
Databáze: OpenAIRE