Studies of insect peptides alloferon, Any-GS and their analogues. Synthesis and antiherpes activity

Autor:	Mariola, Kuczer, Katarzyna, Dziubasik, Anna, Midak-Siewirska, Renata, Zahorska, Mirosław, Łuczak, Danuta, Konopińska
Rok vydání:	2010
Předmět:	Chlorocebus aethiops Animals Insect Proteins Herpesvirus 1 Human Microbial Sensitivity Tests Peptides Antiviral Agents Vero Cells Chromatography High Pressure Liquid Mass Spectrometry
Zdroj:	Journal of peptide science : an official publication of the European Peptide Society. 16(4)
ISSN:	1099-1387
Popis:	The subject of these studies was synthesis and determination of biological properties of a series of insect peptides, such as alloferon, Any-GS and their analogues. The synthesis of 14 peptides was performed by the solid-phase method. Biological effect of these peptides was evaluated by the antiviral test against Human Herpes Virus type 1 (HHV-1) in vitro using a Vero cell line. It was found that the investigated peptides inhibit the replication of HHV-1 in Vero cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9f7f958526bb056b22a9ea66cac94769 https://pubmed.ncbi.nlm.nih.gov/20191606 Zobrazit plný text záznamu Plný text