Development of a rectal sexually transmitted infection (STI) Model in Rhesus macaques using Chlamydia trachomatis serovars E and L

Autor:	Tara R, Henning, Monica, Morris, Shanon, Ellis, Kristen, Kelley, Christi, Phillips, Jana, Ritter, Tara, Jones, Eli, Nachamkin, Cheng Y, Chen, Jaeyoung, Hong, Joseph, Kang, Dorothy, Patton, Janet, McNicholl, John, Papp, Ellen N, Kersh
Rok vydání:	2017
Předmět:	Disease Models Animal Coinfection Rectum Sexually Transmitted Diseases Animals Chlamydia trachomatis Female HIV Infections Simian Immunodeficiency Virus Chlamydia Infections Serogroup Macaca mulatta
Zdroj:	Journal of medical primatology. 46(5)
ISSN:	1600-0684
Popis:	Rectal STI coinfection models enhance the understanding of rectal HIV transmission risk factors.Rhesus macaques (n=9) were exposed to one of three rectal Chlamydia trachomatis (CT) challenges: C. trachomatis LChlamydial infections were successfully established in each animal, with varying degrees of persistence. Mucosal IL-1beta was upregulated in animals consecutively infected with CT-E then CT-LThis study demonstrates successful rectal infection of rhesus macaques with CT-E and CT-L
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9f4e6fd4d23a0f4ce40474f5d5430913 https://pubmed.ncbi.nlm.nih.gov/28488731 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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