| Autor: |
Sabina, Shukurova, Rodina, Sadek, Narmin, Mekawy, Meriem, Bendaoud, Yassine, Yachou, Andrii, Mamchyn, Abdeslem, El Idrissi |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Advances in experimental medicine and biology. 1370 |
| ISSN: |
0065-2598 |
| Popis: |
Taurine, 2-aminoethanesulfonic acid, is one of the most abundant free amino acids especially in excitable tissues, with wide physiological actions. Several lines of evidence suggest that taurine may function as a potent inhibitory neuromodulator that regulate neuronal activity in many cerebral areas. Parenteral injection of kainic acid (KA), a glutamate receptor agonist, causes severe and stereotyped behavioral convulsions in mice and is used as a rodent model for human temporal lobe epilepsy. In the adult brain, inhibitory GABAergic interneurons modulate the activity of principal excitatory cells via their GABA |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
