Autor: |
Sergio, Rodríguez, Litzy Gisella, Bermúdez, Daniel, González, Camila, Bernal, Alejandra, Cañas, Teresa, Morales-Ruíz, Berta, Henríquez, Adriana, Rojas |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Molecular medicine reports. 26(5) |
ISSN: |
1791-3004 |
Popis: |
Cell senescence is a state of limited cell proliferation during a stress response or as part of a programmed process. When a senescent cell stops dividing, maintaining metabolic activity contributes to cellular homeostasis maintenance. In this process, the cell cycle is arrested at the G0/G1 phase. p16INK4A protein is a key regulator of this process via its cyclin‑dependent kinase inhibitor (CDKI) function. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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