Transcriptional regulation of

Autor: Sergio, Rodríguez, Litzy Gisella, Bermúdez, Daniel, González, Camila, Bernal, Alejandra, Cañas, Teresa, Morales-Ruíz, Berta, Henríquez, Adriana, Rojas
Rok vydání: 2022
Předmět:
Zdroj: Molecular medicine reports. 26(5)
ISSN: 1791-3004
Popis: Cell senescence is a state of limited cell proliferation during a stress response or as part of a programmed process. When a senescent cell stops dividing, maintaining metabolic activity contributes to cellular homeostasis maintenance. In this process, the cell cycle is arrested at the G0/G1 phase. p16INK4A protein is a key regulator of this process via its cyclin‑dependent kinase inhibitor (CDKI) function.
Databáze: OpenAIRE