[Dimethindene maleate administered via intramuscular route in man: local and systemic tolerance]

Autor:	V, Arnera, J B, Llull
Jazyk:	francouzština
Rok vydání:	1991
Předmět:	Adult Eosinophils Male Dimethindene Humans Pain Female Injections Intramuscular Blood Chemical Analysis
Zdroj:	Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis. 80(17)
ISSN:	1013-2058
Popis:	Local and systemic tolerance of dimethindene maleate was studied in 10 healthy volunteers by the intramuscular route (4 mg in 4 ml solvent). Subjective perception of pain and other reported side effects were registered and objective signs at the injection site were assessed repeatedly. Hematologic and biochemical tests were performed before and after completion of the study. Two volunteers complained about local pain immediately and one hour after the injection. An other volunteer developed a small hematoma within 48 hours after injection. No other side effects or adverse reactions were noted. Good tolerance of dimethindene maleate after intramuscular application could thus be established.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9e94f4604ace2d04658d942ed868af3c https://pubmed.ncbi.nlm.nih.gov/1871473 Zobrazit plný text záznamu