| Autor: |
V A, Berezovskiĭ, T V, Serebrovskaia, A A, Ivashkevich |
| Rok vydání: |
1987 |
| Předmět: |
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| Zdroj: |
Kosmicheskaia biologiia i aviakosmicheskaia meditsina. 21(1) |
| ISSN: |
0321-5040 |
| Popis: |
Two groups of young healthy men--natives of lowlands who for one year lived and worked in chronic hypoxia (Group 1 at an altitude of 1680 m with PO2 = 120 mm Hg and Group 2 at an altitude of 3650 with PO2 = 90 mm Hg) were examined. It was found that after this prolonged exposure the subjects showed a higher sensitivity of the respiration system to hypoxia, an enhanced lung ventilation and circulation, a lower gas exchange and physical work capacity. The concentration of lactic acid at rest in the Group 2 subjects was 47% higher than in the Group 1 subjects. The lactate/pyruvate ratio in the Group 2 subjects increased by 46% thus indicating an enhanced rate of anaerobic processes. A higher deficiency of buffer bases, a lower concentration of bicarbonates in blood at rest and during exercise tests of the Group 2 subjects pointed to metabolic acidosis. The subjects with a higher rate of anaerobic metabolism in a low PO2 environment displayed a diminished sensitivity of the hypoxic stimulation of respiration, an increased tolerance to the very low PAO2 and a reduced work capacity in chronic hypoxia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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