[Anti-idiotypic antibodies against antibodies to the herpes simplex virus and its early antigens]

Autor:	N P, Kosiakova, R P, Pavliuchenkova, T A, Posevaia
Rok vydání:	1991
Předmět:	Mice Time Factors Virus Cultivation Antibody Specificity Immune Sera Radioimmunoassay Animals Simplexvirus Immunization Rabbits Antibodies Viral Antigens Viral Antibodies Anti-Idiotypic
Zdroj:	Voprosy virusologii. 36(2)
ISSN:	0507-4088
Popis:	Polyclonal anti-idiotypic antibodies (anti-Id-AT or AT2) were produced to AT idiotopes of virion antigens--structural proteins of herpes simplex virus (HSV) and of early virus-induced antigens (VIA). The method of SPRIA established that anti-Id-AT seemed to be associated with AT active centers. Besides, immunization with anti-Id-AT produced anti-anti-Id-AT (AT3) similar in their specificity with antiviral AT or anti-VIA. It was shown that AT2 could be used as a diagnostic preparation instead of specific antigen for the detection of antibody to HSV or VIA in human sera by indirect RIA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9dc765c6145385a3cad5abc8b7f34f68 https://pubmed.ncbi.nlm.nih.gov/1652868 Zobrazit plný text záznamu