Autor:	Nicholas, Cope, Borna, Novak, Christine, Candelora, Kenneth, Wong, Maria, Cavallo, Amber, Gunderwala, Zhiwei, Liu, Yana, Li, Zhihong, Wang
Rok vydání:	2019
Předmět:	Proto-Oncogene Proteins B-raf Imidazoles Enzyme Activators Molecular Dynamics Simulation Kinetics HEK293 Cells Vemurafenib Mutation Oximes Humans Phosphorylation Protein Multimerization Protein Kinase Inhibitors Protein Binding
Zdroj:	Chembiochem : a European journal of chemical biology. 20(22)
ISSN:	1439-7633
Popis:	The most prevalent BRAF mutation, V600E, occurs frequently in melanoma and other cancers. Although extensive progress has been made toward understanding the biology of RAF kinases, little in vitro characterization of full-length BRAF
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9da5ead3fe67b2b06d0b14e9b3bb990e https://pubmed.ncbi.nlm.nih.gov/31152574 Zobrazit plný text záznamu Plný text