Africanized Bee Venom (

Autor: Camila G, Dantas, Ailma O, da Paixão, Tássia L G M, Nunes, Italo J F, Silva, Bruno, Dos S Lima, Adriano A S, Araújo, Ricardo L C, de Albuquerque-Junior, Kátia P, Gramacho, Francine F, Padilha, Luiz P, da Costa, Patricia, Severino, Juliana C, Cardoso, Eliana B, Souto, Margarete Z, Gomes
Rok vydání: 2022
Zdroj: Toxics. 10(10)
ISSN: 2305-6304
Popis: This study evaluated the neuroprotective effects of the Africanized bee venom (BV) and its mechanisms of action after 6-hydroxydopamine-(6-OHDA)-induced lesion in a mice model. Prior to BV treatment, mice received intrastriatal microinjections of 6-OHDA (no induced dopaminergic neuronal death) or ascorbate saline (as a control). BV was administered subcutaneously at different dosages (0.01, 0.05 or 0.1 mg·Kg
Databáze: OpenAIRE