| Autor: |
R, Baretti, B, Schaumann, R, Meyer, D, Alfaouri, R, Hetzer |
| Jazyk: |
němčina |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
Deutsche medizinische Wochenschrift (1946). 125(39) |
| ISSN: |
0012-0472 |
| Popis: |
A 33-year-old man was admitted 7 years after a testicular teratomatous carcinoma had first been diagnosed, treated by a right orchiectomy and two-stage radical retroperitoneal lymphadenectomy. Five years later the first mediastinal metastases were treated with high-dosage chemotherapy and autologous germ-cell transplantation, and remaining paraaortic--mediastinal tumour tissue was resected. Two years later another tumour at that site was only partially resected. A curing treatment seemed impossible, because the aortic wall had been invaded.Five months after re-thoracotomy the metastasis and the invaded aortic segment were resected, the latter replaced by a vascular prosthesis. Histology indicated metastasis of a malignant teratoma of intermediate type. There has been no evident recurrence in the last 20 months.Combined orchidectomy, lymphadenectomy, high-dosage chemotherapy with cisplatin and autologous germ-cell transplantation at present constitute the standard treatment of malignant testicular germ-cell tumour. In case of metastatic infiltration of vital structures, such as the aortic wall, special operative procedures can prolong the period of remission when the success of a standard treatment seems limited. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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