Autor: |
Leander, Malich, Falk, Gühne, Tobias, Hoffmann, Ansgar, Malich, Tobias, Weise, Peter, Oelzner, Gunter, Wolf, Martin, Freesmeyer, Alexander, Pfeil |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
RMD open. 8(2) |
ISSN: |
2056-5933 |
Popis: |
Giant cell arteritis (GCA) with the involvement of extracranial vessels is increasingly coming into focus. Isolated aortic involvement in the acute phase of GCA is probably more frequent than estimated because only a minority of patients show typical symptoms.The study included 60 patients with GCA at the onset of a GCA. All patients had undergone a PET/CT scan. 44 patients were GC naïve and 16 patients received GC.The most affected arteries were the ascending aorta (72%), followed by the brachiocephalic trunk (62%), aortic arch (60%) and descending aorta (60%). The aorta and its branches showed an inflammatory involvement in 83.3% of patients. A singular affection of the aorta and the brachiocephalic trunk was revealed in 20% of cases. GC-naïve patients (95.5%) had more frequently affected arteries compared with GC-treated patients (50%).Our study showed the frequent involvement of the thoracic aorta and brachiocephalic trunk in patients with GCA using PET/CT. Since these vascular compartments cannot be visualised by ultrasound, we advocate screening imaging of the aorta with PET/CT when GCA is suspected. Because the use of GC is associated with a marked decrease in the inflamed vascular segment in GCA, PET/CT should be performed as soon as possible. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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