[Chronic pain: medico-biologic and sotsio-economic aspects]
Autor: | N N, Iakhno, M L, Kukushkin |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Vestnik Rossiiskoi akademii meditsinskikh nauk. (9) |
ISSN: | 0869-6047 |
Popis: | In this article the role of neurobiological, psychological and social factors in pathogenesis of chronic pain is analyzed. The chronic pain is considered not as a symptom of damage of tissue and as independent illness due to non-adequate neuroplasticity of systems involved into regulation of pain sensitivity. The major role in development and maintenance of chronic pain is devoted to the primary genetically determined and/or secondary disturbance of interaction between nociceptive and antinociceptive systems at various levels--from peripheral neuron to central structures--that provides pain perception and painful behaviour development. |
Databáze: | OpenAIRE |
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