[Molecular mechanisms of radiation death of lymphoid cells. Protein poly-ADP-ribosylation in thymocyte fractions]

Autor: N I, Sorokina, M A, Spiridonov, I V, Filippovich, E F, Romantsev
Rok vydání: 1983
Předmět:
Zdroj: Radiobiologiia. 23(6)
ISSN: 0033-8192
Popis: A study was made of the process of poly-ADP-ribosylation of proteins in cells of radioresistant and radiosensitive fractions of mouse thymus lymphocytes after irradiation of isolated cells with a dose of 25 Gy. It was shown that activation of ADP-ribosylation of proteins occurred simultaneously with the formation of single-strand DNA breaks in thymocytes, and the degree of activation in radioresistant and radiosensitive fractions was nearly the same.
Databáze: OpenAIRE