[Role of adjuvant chemotherapy in the treatment of medulloblastoma in children]

Autor:	N V, Sachivko, N E, Konoplia, S V, Petrovich, E V, Sharak
Rok vydání:	2002
Předmět:	Male Time Factors Adolescent Age Factors Antineoplastic Agents Radiotherapy Dosage Combined Modality Therapy Survival Analysis Carboplatin Sex Factors Chemotherapy Adjuvant Lomustine Child Preschool Humans Female Cisplatin Cerebellar Neoplasms Child Antineoplastic Agents Alkylating Medulloblastoma
Zdroj:	Voprosy onkologii. 48(3)
ISSN:	0507-3758
Popis:	A retrospective review was carried out to evaluate the results of treatment (1989-1998) of 81 children, aged under 15, with primary medulloblastoma. Thirty-three patients received surgery and postoperative craniospinal radiotherapy; 48--adjuvant chemotherapy (VCR 1.5 mg/m2, i.v., 1 day; CCNU 75 mg/m2, per os, 1 day; cisplatin 80 mg/m2 or carboplatin 400 mg/m2, i.v., 1 day). Overall 9-year survival was 37 +/- 0.8%. This index in the adjuvant chemotherapy group was 59 +/- 0.8%, without chemotherapy--22 +/- 0.8%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9d27a1a84bfe5786778b496e9f62a913 https://pubmed.ncbi.nlm.nih.gov/12455354 Zobrazit plný text záznamu