[The effect of naloxone on rhythm disorders and on the conduction system of the heart]

Autor:	E V, Shliakhto, A A, Zaĭtsev, A V, Panov, A V, Ardashev, E M, Nifontov, E A, Kashina, V V, Kazarin, V V, Ivanov
Rok vydání:	1996
Předmět:	Adult Male Dose-Response Relationship Drug Naloxone Cardiac Pacing Artificial Drug Evaluation Preclinical Arrhythmias Cardiac Disease Models Animal Electrocardiography Heart Conduction System Reference Values Animals Humans Rabbits Anti-Arrhythmia Agents
Zdroj:	Eksperimental'naia i klinicheskaia farmakologiia. 59(3)
ISSN:	0869-2092
Popis:	In experimental arrhythmias induced in rabbits by strophanthin, epinephrine, and calcium chloride the high antiarrhythmic efficacy of Naloxone was proved. No antiarrhythmic activity of Naloxone was observed in aconitine models. The intravenous administration of Naloxone to normal adults (0.4 - 0.8 mg) increased the sinus cycle length, sinus node recovery time (SNRT), CSNRT, and sinoatrial conduction time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9d0d2046efbbca6323e108c95e732331 https://pubmed.ncbi.nlm.nih.gov/8974581 Zobrazit plný text záznamu