Autor: |
M A, Stashkevich, E V, Khomutov, O P, Shatova, Iu V, Dumanskiĭ, I I, Zinkovich |
Rok vydání: |
2013 |
Předmět: |
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Zdroj: |
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 85(4) |
Popis: |
In blood plasma of 8 healthy volunteers with resuspended lymphocytes incubated with 5-fluorouracil (5-FU) the drug distribution between cells and liquid was assessed by means of HPLC. Rapid accumulation of 5-FU in lymphocytes was proved (the drug concentration on the 3-rd minute is 2.5-fold higher than in plasma) as well as the absence of temporal changes of 5-FU content both in lymphocytes and blood plasma during 30 minutes of experiment. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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