[The polyethylene oxide correction of the hemodynamic sequelae in the infusion therapy of massive blood loss]

Autor: G A, Chernysheva, L K, Novikova, M B, Plotnikov
Rok vydání: 1994
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia farmakologiia. 57(5)
ISSN: 0869-2092
Popis: High molecular weight polyethylene oxides (2 x 10(6), 4 x 10(6), and 6 x 10(6)) were tested for their effects on blood pressure, cerebral circulation in rats with massive hemorrhage and turbulent blood flow velocity in the pre- and posthemorrhagic and polyglucine posttreatment. Polyethylene oxide (4 x 10(6) and 6 x 10(6)) alleviated hypotension and cerebral hypoperfusion, which appeared 0.5-1 hour after polyglucine therapy and increased turbulent blood flow velocity. Polyethylene oxide failed to affect spontaneous and alcian blue-induced red blood cell aggregation.
Databáze: OpenAIRE