Popis: |
High molecular weight polyethylene oxides (2 x 10(6), 4 x 10(6), and 6 x 10(6)) were tested for their effects on blood pressure, cerebral circulation in rats with massive hemorrhage and turbulent blood flow velocity in the pre- and posthemorrhagic and polyglucine posttreatment. Polyethylene oxide (4 x 10(6) and 6 x 10(6)) alleviated hypotension and cerebral hypoperfusion, which appeared 0.5-1 hour after polyglucine therapy and increased turbulent blood flow velocity. Polyethylene oxide failed to affect spontaneous and alcian blue-induced red blood cell aggregation. |