| Autor: |
Ahmed, Abbaskhan, Muhammed Iqbal, Choudhary, Mohammed Nabeel, Ghayur, Zeba, Parween, Farzana, Shaheen, Anwar-ul-Hassan, Gilani, Takuro, Maruyama, Kiran, Iqbal, Yoshisuke, Tsuda |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Phytotherapy research : PTR. 26(5) |
| ISSN: |
1099-1573 |
| Popis: |
In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) SantapauWagh; Umbelliferae), the fractionation of the 80% MeOH-H(2) O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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