Germ cell malignancies of the ovary: treatment with vinblastine, actinomycin D, bleomycin and cisplatin containing chemotherapy combinations

Autor:	J E, Bradof, T B, Hakes, M, Ochoa, R, Golbey
Rok vydání:	1982
Předmět:	Adult Ovarian Neoplasms Clinical Trials as Topic Adolescent Antineoplastic Agents Neoplasms Germ Cell and Embryonal Vinblastine Drug Administration Schedule Bleomycin Dactinomycin Humans Drug Therapy Combination Female Cisplatin Cyclophosphamide Follow-Up Studies
Zdroj:	Cancer. 50(6)
ISSN:	0008-543X
Popis:	Seventeen patients with malignant ovarian germ cell tumors were treated with vinblastine, actinomycin D, bleomycin and cisplatin containing combinations. Many of these patients were heavily pretreated. Thirteen patients had objectively measurable disease and ten (77%) had an objective response (CR or PR). Four patients had nonmeasurable disease or were treated in an adjuvant setting and all remain without evidence of disease. Extensive disease and poor performance status were poor prognostic factors. Induction portions of these treatment programs which contained cisplatin appeared most effective. Maintenance portions without cisplatin appeared less effective.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9b193c3f28910f492604df626ccdd9d9 https://pubmed.ncbi.nlm.nih.gov/6179591 Zobrazit plný text záznamu Plný text