Contribution of two-pore K
| Autor: | Sam, Chai, Xiaoping, Wan, Drew M, Nassal, Haiyan, Liu, Christine S, Moravec, Angelina, Ramirez-Navarro, Isabelle, Deschênes |
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| Rok vydání: | 2017 |
| Předmět: |
Heart Failure
Male Gene Expression Profiling Heart Ventricles Induced Pluripotent Stem Cells Myocardial Ischemia Action Potentials Arrhythmias Cardiac Cell Differentiation Real-Time Polymerase Chain Reaction Transfection Cell Line Potassium Channels Tandem Pore Domain Case-Control Studies Humans Female Myocytes Cardiac RNA Interference Signal Transduction Research Article |
| Zdroj: | American journal of physiology. Heart and circulatory physiology. 312(6) |
| ISSN: | 1522-1539 |
| Popis: | Two-pore K+ (K2p) channels are traditionally regarded as merely background leak channels in myriad physiological systems. Here, we describe the expression profile of K2p channels in human-induced pluripotent stem cell-derived cardiomyocytes and outline a salient role in cardiac repolarization and pathology for multiple K2p channels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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