| Autor: |
Jeanmarie R, Gonzalez, Anna, Celli, Antonin, Weckel, Miqdad O, Dhariwala, Geil R, Merana, Oluwasunmisola T, Ojewumi, Joy, Okoro, Laura R, Dwyer, Victoria M, Tran, Jason M, Meyer, Theodora M, Mauro, Tiffany C, Scharschmidt |
| Rok vydání: |
2022 |
| Zdroj: |
The Journal of investigative dermatology. |
| ISSN: |
1523-1747 |
| Popis: |
Filaggrin mutations underlie ichthyosis vulgaris and increased risk of atopic dermatitis, conditions typified by disruption of the skin microbiome and cutaneous immune response. Yet, it remains unclear if neonatal skin barrier compromise due to filaggrin deficiency alters the quality of commensal-specific T cells and the functional impact of such responses. To address these questions, we profiled changes in the skin barrier and early cutaneous immune response of neonatal C57BL/6 Flg |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
