Paroxetine treatment of aggression and self-injury in persons with mental retardation
| Autor: | P A, Davanzo, T R, Belin, M H, Widawski, B H, King |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Stereotypic Movement Disorder Comorbidity Middle Aged Severity of Illness Index Drug Administration Schedule Aggression Paroxetine Treatment Outcome Intellectual Disability Humans Female Prospective Studies Autistic Disorder Self-Injurious Behavior Selective Serotonin Reuptake Inhibitors Follow-Up Studies |
| Zdroj: | American journal of mental retardation : AJMR. 102(5) |
| ISSN: | 0895-8017 |
| Popis: | An open, prospective assessment of the treatment of severe aggression and self-injurious behavior (SIB) with paroxetine, a serotonin re-uptake inhibitor, in 15 institutionalized persons with mental retardation was undertaken. Frequency and severity of aggression and SIB were charted by trained staff members. Only aggression severity was reduced over the entire 4-month follow-up period. Within the limits of an open trial, this effect was significant at one month but did not remain significant subsequently. The apparent diminution of effectiveness after 4 weeks of treatment may suggest adaptive changes warranting further study. |
| Databáze: | OpenAIRE |
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