| Autor: |
Sabine, Pain, Nicolas, Berthélémy, Corinne, Naudin, Véronique, Degrave, Valérie, André-Frei |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Journal of cosmetic science. 69(3) |
| ISSN: |
1525-7886 |
| Popis: |
Photoageing, also called actinic ageing, is the main cause of prematurely aged skin. Our expertise in elastic fibers has led us to discover a process triggered in response to ultraviolet (UV) light and which upsets the balance of elastin fibers: there is too much elastin and insufficient lysyl oxidase (LOXL1) enzyme to form functional elastic fibers. This imbalance then leads to an accumulation of nonfunctional elastin, which forms aggregates. In addition to this imbalance, UV rays also induce elafin synthesis by fibroblasts. Known to be a marker of elastotic aggregates, elafin crystallizes the elastin fibers and stimulates the formation of aggregates that cannot be naturally eliminated by the skin. We developed a |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
